Can the protocol or screening settings be changed after screening begins?

Some protocol or screening settings can be updated after screening begins, but this should be treated as a controlled workflow change rather than a casual edit. Changes to eligibility criteria, decision categories, reviewer assignment, AI settings, or full-text configuration can affect how old and new records are interpreted.

If a change is made after screening has started, earlier decisions may not automatically represent the new criteria. Depending on the project, users may need to rerun AI support, reassign records, re-screen affected studies, or document why previous decisions remain valid.