Can AI act as an independent second reviewer?

Yes, where AI Screener mode is configured. In this mode, AI can act as an independent reviewer stream alongside a human reviewer. The AI output can then be compared with human screening decisions in a way that resembles double screening.

The team configures the AI run, provides the criteria, reviews disagreements, and decides how conflicts are resolved. AI decisions become part of the reviewable workflow record, with final inclusion and exclusion decisions kept under human governance.

AI as a second reviewer can be useful for scale and consistency, but teams should pilot the setup, confirm the protocol fit, and document how AI-generated decisions were used.


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